Case On Heart Failure With Type 2 Diabetes Mellitus Patients with diabetes mellitus have >2× the risk for developing heart failure (hf; hf with reduced ejection fraction and hf with preserved ejection fraction). cardiovascular outcomes, hospitalization, and prognosis are worse for patients with diabetes mellitus relative to those without. beyond the structural and functional changes that characterize diabetic cardiomyopathy, a complex. Type 2 diabetes mellitus is a risk factor for incident heart failure and increases the risk of morbidity and mortality in patients with established disease. secular trends in the prevalence of diabetes mellitus and heart failure forecast a growing burden of disease and underscore the need for effective therapeutic strategies. recent clinical trials have demonstrated the shared pathophysiology.
Heart Failure In Type 2 Diabetes Mellitus Circulation Research Diabetes mellitus (dm) is a major risk factor for several cardiovascular (cv) outcomes, including heart failure (hf) [1, 2]. epidemiological and observational studies have demonstrated that dm increases the risk for new onset hf independent of other traditional risk factors. each 1% increase in glycated hemoglobin a1c is associated with a 30%. Heart failure (hf) risk is significantly increased in diabetes. type 2 diabetes mellitus (t2dm) is a global epidemic and is expected to affect over 592 million people worldwide by 2035, a dramatic increase from 382 million people with diabetes in 2013 1, a prevalence that is likely underestimated 2. Type 2 diabetes is one of the most relevant risk factors for heart failure, the prevalence of which is increasing worldwide. the aim of the review is to highlight the current perspectives of the pathophysiology of heart failure as it pertains to type 2 diabetes. this review summarizes the proposed mechanistic bases, explaining the myocardial damage induced by diabetes related stressors and. Metformin and sglt 2 (sodium glucose cotransporter type 2) inhibitors, are preferable to use of sulfonylurea drugs in patients at high risk for hf and those with established hf. insulin is sometimes required to achieve adequate glycemic control in individuals with dm and hf. insulin use is associated with weight gain and risk of hypoglycemia.
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