Swan A Python Library For The Analysis And Fairlie Reese Irna We introduce the swan python library, which is designed to analyze and visualize transcript models. results: swan finds 4909 differentially expressed transcripts between cell lines hepg2 and hffc6, including 279 that are differentially expressed even though the parent gene is not. additionally, swan discovers 285 reproducible exon skipping and. Swan is a python library i developed for the visualization and analysis of long read transcriptomes. swan can produce unique graph based visualizations of splicing within genes. swan can additionally perform differential gene and transcript expression testing, find isoform switching genes, and find novel intron retention and exon skipping.
Swan вђ Fairlie Reese Swan: a python library for the analysis and visualization of long read transcriptomes fairlie reese irna ismb 2020 posters. Of the differentially expressed transcripts, 279 belong to a parent gene that is not differentially expressed and are therefore candidates for isoform switching analysis. in addition, swan found 285 novel exon skipping events and 47 novel intron retention events. swan provides a platform for deeply exploring full length transcriptome data. Swan is a python library designed for the analysis and visualization of transcriptomes, especially with long read transcriptomes in mind. users can add transcriptomes from different datasets and explore distinct splicing and expression patterns across datasets. Motivation long read rna sequencing technologies such as pacbio and oxford nanopore have discovered an explosion of new transcript isoforms that are difficult to visually analyze using currently available tools. we introduce the swan python library, which is designed to analyze and visualize transcript models. results swan finds 4,909 differentially expressed transcripts between cell lines.
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